Incorporating baseline functional status to improve validity of neurological outcome assessments following cardiac arrest
نویسندگان
چکیده
منابع مشابه
Mild Resuscitative Hypothermia to Improve Neurological Outcome After Cardiac Arrest A Clinical Feasibility Trial
Background and Purpose—Recent animal studies showed that mild resuscitative hypothermia improves neurological outcome when applied after cardiac arrest. In a 3-year randomized, prospective, multicenter clinical trial, we hypothesized that mild resuscitative cerebral hypothermia (32°C to 34°C core temperature) would improve neurological outcome after cardiac arrest. Methods—We lowered patients’ ...
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AIM OF STUDY To determine if a new protocol can increase the detection of agonal respirations by emergency medical dispatchers and thus the presence of cardiac arrest. METHODS This is a prospective before and after study performed in a large metropolitan city. Cases were identified by review of all cardiac arrests called into a central medical control office. Data were collected through revie...
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BACKGROUND AND PURPOSE Current guidelines suggest that cardiac arrest (CA) survivors should be ventilated with 100% O(2) after resuscitation. Breathing 100% O(2) may worsen neurological outcome after experimental CA. This study tested the hypothesis that graded reoxygenation, with oximetry guidance, can safely reduce FiO(2) after resuscitation, avoiding hypoxia while promoting neurological reco...
متن کاملTherapeutic hypothermia and neurological outcome after cardiac arrest.
INTRODUCTION/AIM The most important clinically relevant cause of global cerebral ischemia is cardiac arrest. Clinical studies showed a marked neuroprotective effect of mild hypothermia in resuscitation. The aim of this study was to evaluate the impact of mild hypothermia on neurological outcome and survival of the patients in coma, after cardiac arrest and return of spontaneous circulation. M...
متن کاملSerum tau and neurological outcome in cardiac arrest
OBJECTIVE To test serum tau as a predictor of neurological outcome after cardiac arrest. METHODS We measured the neuronal protein tau in serum at 24, 48, and 72 hours after cardiac arrest in 689 patients in the prospective international Target Temperature Management trial. The main outcome was poor neurological outcome, defined as Cerebral Performance Categories 3-5 at 6 months. RESULTS Inc...
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ژورنال
عنوان ژورنال: Resuscitation
سال: 2019
ISSN: 0300-9572
DOI: 10.1016/j.resuscitation.2019.07.006